Hopefully there is a new formulation of sumatriptan(brand=Imitrex) coming..it is a skin patch of sumatriptan, that is a relatively low dose, few side effects…it lasts a long time, maybe very good for long, prolonged migraines. The only side effect that is worrisome is an occasional skin rash. This bypasses the GI system, which is a problem(due to slowing of the gut during a migraine) with tablets..the tablets often just sit down there and do not get absorbed very quickly. This sumatriptan patch(from NuPathe Pharm..) may be useful for those with chronic(frequent) migraines……

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