by Sue Robbins | Nov 27, 2019 | Migraine
Ergotamine has historically been used to treat migraine since the middle ages, and as a pharmaceutical since 1926,1 but is limited by poor tolerability (nausea, vomiting, and cardiovascular effects), thus attempts were made to synthesize compounds with the same...
by Dr Robbins | Nov 24, 2012 | Headache Drugs
Apparently the FDA has agreed to review the long-awaited drug application for MAPP Pharmaceutical’s inhaled form of dihydroergotamine(DHE), Levadex. DHE has been a very good migraine as needed….abortive…drug since 1945, with very few serious side...