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Circadian and Seasonal Variation of Migraine Attacks in Children
Soriani S, Fiumana E, et al.
Posted: January 2007  
Headache 2006;46:1571-1574

Object:   To investigate the rhythmicity of migraine episodes without aura in a pediatric population.

Methods:   Time of occurrence of 2517 migraine attacks in 115 children was recorded, by means of a diary, both by hourly and monthly intervals.

Results:   A significant circadian variation, characterized by a peak in the afternoon and one in the early morning was found. A seasonal peak was also observed between November and January, while a nadir was observed in July.

Conclusions:   The clustering of attacks in the morning and midday and in autumn-winter, with a minimum frequency in July, suggests that school activities may represent an important cause of migraine.