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Migraines Linked to Intrapulmonary Right-to-Left Shunt
Thenganatt J, Schneiderman J, Hyland RH, et al.
Posted: May 2006
Objective: To determine if there is an association
between migraines and intrapulmonary right-to-left shunt.
Background: Several studies have described an association
between migraines and intracardiac right-to-left shunt.
Methods: Patients with hereditary hemorrhagic
telangiectasia (HHT) were retrospectively recruited from the Toronto
Hereditary Hemorrhagic Telangictasia Center Clinical Database. All patients
had been prospectively, systematically asked about a history of migraines
and systematically screened for pulmonary and cerebral arteriovenous
malformations (AVMs). All patients with a definite diagnosis of HHT,
assessed during a 2-year period were included. Univariate analyses and logistic
regression were performed, for migraine as the dependent variable ad the
following independent variables: age, sex, pulmonary AVMs, and cerebral AVMs.
Conclusions: There is a significant association between
intrapulmonary right-to-left shunt and migraine.