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Comparative Study of Anxiety, Depression, Somatization,
Functional Disability, and Illness Attribution in
Adolescents with Chronic Fatigue or Migraine
Smith MS, Martin-Herz SP, Womack WM, Marsigan JL.
Posted: September 2004
Objective: To compare adolescents
with migraine, unexplained profound chronic fatigue of >6 months
duration, and normal school controls on measures of anxiety,
depression, somatization, functional disability, and illness
Methods: Adolescents referred to Children’s
Hospital and Regional Medical Center for behavioral treatment
of migraine or evaluation of chronic fatigue were compared with
a group of healthy controls of similar age and sex from a
middle school. Migraine and fatigued subjects completed an
illness attribution questionnaire.
Conclusions: Adolescents referred to an
academic center for evaluation of unexplained chronic fatigue
had greater rates of school absenteeism than adolescents with
migraine or healthy controls. Those meeting Centers for
Disease Control and Prevention criteria for chronic fatigue
syndrome had higher anxiety scores than controls and higher
depression and somatization scores than migraineurs or controls.
Parents of adolescents with idiopathic chronic fatigue
syndrome were less likely to endorse psychological factors
as possibly contributing to their symptoms than parents of
adolescents with Centers for Disease Control and Prevention
criteria for chronic fatigue syndrome or migraine.