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Migraine is Associated with Menorrhagia and
Tietjen G.D., et al.
Posted August 2003
Presented at: 45th Annual Scientific Meeting
American Headache Society
June 19-22, 2003; Chicago, Illinois
Objectives: To evaluate the frequency of menorrhagia and endometriosis
in female migraineurs compared to age-matched controls.
Conclusions: Migraineurs have a higher frequency of endometriosis,
menorrhagia, and associated psychosocial consequences. These findings suggest
that in the female migraine population there should be further study of factors
(e.g., eicosanoids, platelet function) which influence endometriosis and menstrual
blood flow. The findings of menorrhagia, increased bruising, and rectal bleeding
are intriguing given the fact that in women of childbearing age migraine is
reported to be an ischemic stroke risk factor, and hypercoagulability has been